Margalit Mitzner
Education:
B.S. Brandeis University (2021)
Current Position:
4th Year MSTP
2nd Year Graduate Student
Advisor:
Prateek Prasanna (Chao Chen Co-Mentor)
Graduate Program:
Biomedical Informatics
Research Interests:
I am interested in integrating basic science, clinical, and computational research methods to study how best to improve diagnosis, management, and treatment of disease, aiming toÌýimprove patient care in both the short- and the long-term. Previously, I’ve studied limb regeneration in axolotl salamanders, pancreatic beta cell senescence in mice, and the organization and ultrastructure of the synaptic periactive zone at theÌýDrosophilaÌýneuronal synapse. More recently, I’ve studied ocular diseases such as diabetic retinopathy and diabetic macular edema (DME), analyzing response to anti-VEGF injections in patient eyes with DME as well as working to develop methods to improve diagnosis and treatment of these conditions through identifying and quantifying relevant biomarkers in the circulation and ocular fluids.
Publications:
Fickweiler, W., Chokshi, T. Jangolla, S., Mitzner, M., Wu, I., Park, H.; Park, K.; Aiello, L.P., Sun, J., King, G. L. Clinical Characterization Of Aqueous And Vitreous Retinol-Binding Protein 3 Concentrations In Relation To Diabetic Retinopathy Severity, Retinal Structures, And Systemic Complications. Retina 44(6):p 1026-1033 (2024, June). DOI: 10.1097/IAE.0000000000004059.
Mitzner, M. G., Bhattacharya, M., Gutta, R., Chen, C., Gadgeel, S.M., and Prasanna, R. "Geometric features of pulmonary arteries are associated with early progression and progression-free survival in small-cell lung cancer patients treated with chemotherapy and immunotherapy", Proc. SPIE 12927, Medical Imaging 2024: Computer-Aided Diagnosis, 129270A (2024, April 3); .
Loewenthal J., Innes K.E., Mitzner M., Mita C., Orkaby A.R. Effect of Yoga on Frailty in Older Adults: A Systematic Review. Ann Intern Med. (2023, Mar 14). doi: 10.7326/M22-2553. Epub ahead of print. PMID: 36913687.
Fickweiler W., Mitzner M., Jacoba C.M.P., Sun J.K. Circulatory Biomarkers and Diabetic Retinopathy in Racial and Ethnic Populations. Semin Ophthalmol. (2023, January 29):1-11. doi: 10.1080/08820538.2023.2168488. Epub ahead of print. PMID: 36710371.
Signore S.J.D., Mitzner M.G., Silveira A.M., Fai T.G., Rodal A.A. An approach for quantitative mapping of synaptic periactive zone architecture and organization. Mol Biol Cell. (2022, December 21). mbcE22080372. doi: 10.1091/mbc.E22-08-0372.Ìý
Fickweiler, W., Park, H., Park, K., Mitzner, M.G., Chokshi, T., Boumenna, T., Gautier, J., Zaitsu, Y., Wu, I., Cavallerano, J., Aiello, L.P., Sun, J.K., King, G.L. (2022, September 1). Elevated Retinol Binding Protein 3 Concentrations Are Associated With Decreased Vitreous Inflammatory Cytokines, VEGF, and Progression of Diabetic Retinopathy. Diabetes Care; 45 (9): 2159–2162. .Ìý
Jacoba, C.M.P., Mitzner, M., Cavallerano, J., Silva, P.A.S., Bhagat, N., Zarbin, M.A., Aiello, L.P., Elmasry, M.A. (2022, February 20). Diabetic Macular Edema. American Academy of Ophthalmology, EyeWiki. .Ìý
Jacoba, C.M.P., Mitzner, M., Robinson, D., Silva, P.A.S., Sun, J.K., Elmasry, M.A. (2021, October 20). Diabetic Macular Ischemia. American Academy of Ophthalmology, EyeWiki. .Ìý
Apiki, J., Yuanwei Cheng, J., Soslowsky, R., Rosencwaig, M., Chernobelsky, E., Mitzner, M. (2021, January 14). How to Train an Undergraduate Researcher in The Age of COVID-19. FocalPlane. .